One-seed juniper was commonly employed medicinally by a number of native North American Indian tribes, who used it to treat a variety of complaints[257]. It is little, if at all, used in modern herbalism. The leaves are febrifuge, laxative and pectoral[216]. An infusion is used in the treatment of stomach complaints, constipation, coughs and colds[216]. An infusion was also used by pregnant women prior to childbirth in order to relax the muscles[257]. A poultice of the heated twigs can be bound over a bruise or sprain in order to reduce the swelling[257]. An infusion of the staminate cones has been used as a stomach tonic and in the treatment of dysentery[257]. The chewed bark has been applied externally to help heal spider bites[257]. It is also highly prized as a dressing on burns[257]. The fruits are strongly diuretic[257]. A gum from the plant has been used as a temporary filling in a decayed tooth[257].